Restless Legs Syndrome (RLS) Discussion Board

... has there been good studies on the efficacy of Horizant vs Requip for severe RLS? I will try research this tomorrow. . I'm not sure about studies of Horizant vs Requip in severe RLS. I suspect there are studies for mild RLS. My statement is made on the basis of reading perhaps 100,000 posts on ...

Brendan, I'm glad you found us. Sounds like you have a fair handle on what's happening to you. Severe RLS with augmentation. Those of us who have been through it know what torture it is. Using Horizant would be in line with standard augmentation options. However, Horizant is almost never a strong en...

Holland, you say you take Kratom 720mg at 8pm and then again during the night. ... Im interested that you do so well on only 1.5 grams... Well, remember that nearly all my RLS symptoms are controlled with the IV Iron infusions. Also, I seem a little more sensitive to most drugs than average, mostly...

Holland, what are you taking for WED now? I am sure you have it written here somewhere, apologies for asking. Are you still taking dipyridamole? Nothing for urge to move. Urge to move is almost non-existent. I had been occasionally using THC for sleep, but after reading the last article on opioid f...

Not much discussion in the article, but every little bit of information helps scientists get closer to the causes and treatment possibilities.

Welcom dwhite00. I'm glad you found us. Sounds like you are doing well. I hope it continues. You didn't say what your current dose of pramipexole is, but likely you are above the max current recommended dose, which is much lower than the FDA approved doses. This means that you are likely to develop ...

Good news update: I saw my doc a few days ago for BP check. Got lab done at same time. Ferritin 477, Transferrin Sat=42%. This is 26 weeks after my second set of Injectafer infusions. My ferritin was 260 at 22 weeks after my first set, and at that time was having recurrence of urge to move symptoms,...

Most of the "nighttime" cold meds have diphenhydramine (Benadryl) in them. Avoid them like the plague.

...he felt the patch was better. It is ordered and should be here next week.... Now to see if the medicine works, Be aware that Neupro patches are expensive. Not only that, 30-40% of people can't use them because of the severe rashes that are common. Additionally, augmentation occurs as well. For t...

Hi Wendykat, glad you found us. I hope you find what you are looking for. We have lots of knowledgeable, compassionate, empathetic people here. Let us know if you have problems.

The official dosing for ropinirole and pramipexole (Requip and Mirapex) are way too high and lead to frequent augmentation. RLS experts keep the doses of these dopamine agonists as low as possible to prevent this (and the other serious side effects).

Yup, ropinirole is the generic name for Requip. Maybe your doc just forgot that you had tried it before, or perhaps he feels the combination would be better than either alone, which it is. Either way, I would start with a smaller dose (1/2 tablet) for at least a few days.

meghcelmayster, Welcome to the RLS community. Thanks for the information. Others have tried potassium without much improvement. I'm happy you are better and hope it continues. If your symptoms return, be sure and post information here, likely someone here will have helpful suggestions.

Studies have shown that doctors are most influenced by their experience, INITIAL training and one-on-one discussions with other doctors. Newer scientific evidence is lower down on the list. Most doctors have had no experience with IV Iron for RLS, their initial training was very likely "iron is...

One thing to bear in mind, the doses of opioids used for RLS are generally quite a bit less than the doses used for pain, and side effects are less as well (usually).