Search found 95 matches

by wantok
Wed Jun 24, 2020 11:12 pm
Forum: Prescription Medications
Topic: Gabapentin--Lyrica--Horizant?
Replies: 1
Views: 57

Gabapentin--Lyrica--Horizant?

Anyone heard of anyone who got depressed on both gabapentin and lyrica, NOT get depressed on Horizant? (I know we are all different.)
by wantok
Tue May 19, 2020 10:24 pm
Forum: Prescription Medications
Topic: Lyrica -- glutamate -- Gabapentin
Replies: 3
Views: 86

Re: Lyrica -- glutamate -- Gabapentin

Thanks for looking into this. From how I read the first quote, does it assume or imply that Gabapentin "decreases" glutamate? It doesn't sound very declarative; more like it "should be expected to." It certainly is possible I am not understanding what I am reading. "Mean glutamate concentrations did...
by wantok
Tue May 19, 2020 4:08 pm
Forum: Prescription Medications
Topic: Lyrica side effects
Replies: 9
Views: 192

Re: Lyrica side effects

Thanks. I confess after years of failure and being borderline suicidal from the sleep deprivation/crazy nights I have a hard time not being very invested in success/failure of Lyrica which I have not experienced on any other of the dozens of therapies attempted in a decade plus. I wrote about this p...
by wantok
Tue May 19, 2020 4:00 pm
Forum: Prescription Medications
Topic: Lyrica -- glutamate -- Gabapentin
Replies: 3
Views: 86

Lyrica -- glutamate -- Gabapentin

I was given Gabapentin more than one time and kept increasing the dose to a point where I got depresssed before it was stopping my leg movements (PLMs). I was told by Dr. B that I would get depressed on Lyrica so he recommended not to bother trying it. I tried it and at the lowest dose, from the fir...
by wantok
Sat May 16, 2020 2:51 pm
Forum: Prescription Medications
Topic: Lyrica side effects
Replies: 9
Views: 192

Re: Lyrica side effects

Thanks. Had to go back up to 175 because of PLMs mid-night. Pattern is I will stay at 175 tonight and it won't work well and I will be up to 200. Then 3 good nights on 200, and repeat. Fear this will happen until I can't go up or some side effect will make Lyrica impossible to take altogether. A few...
by wantok
Fri May 15, 2020 1:06 pm
Forum: Prescription Medications
Topic: Lyrica side effects
Replies: 9
Views: 192

Re: Lyrica side effects

Reduced dosage worked, at least the first night.
by wantok
Thu May 14, 2020 3:51 pm
Forum: Prescription Medications
Topic: Lyrica side effects
Replies: 9
Views: 192

Lyrica side effects

I have had a wonderful experience with Lyrica (longer story in other posts) but this weird thing is happening and I am wondering if others have any input about it. I have had to increase it, usually after around 5 days at each dose to continue to control the shaky legs. Then at the increased dose, t...
by wantok
Thu May 07, 2020 2:29 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Update: Went up to 150mg nightly (only) on the Lyrica. I have been taking it for over a month, maybe two months now. As I said in earlier post, the experiment of going off of it for two days every week was not good for me so I had been increasing the dose every 4-5 days and was worried about side ef...
by wantok
Tue Apr 28, 2020 7:38 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Problem now isn't depression (yet) but the dosage needs to be increased every 4 days to continue to be effective. It worries me, of course, because I think I'll either get depressed on the higher dosages or I'll get to the maximum safe dose and then it will only work for 4 days. I worry because it w...
by wantok
Sat Apr 25, 2020 1:43 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Thank you for your kind thoughts. I am not alone in having these medication issues. It has helped me over the years to think of this community. It has been an immeasurable help to me in so many ways. Had another good night, but only my fourth on 100 mg of lyrica (+ marijuana). My husband sleeps like...
by wantok
Fri Apr 24, 2020 1:14 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Beth: Iron: I get iron injections one or two times annually. My ferritin is kept high. Opiods: I loved methadone. Worked great for sleeping like a baby but even at 5mg I also was totally sedated all day and then serious depression set in. The others mostly alerted me big time unfortunately. Very bad...
by wantok
Sun Apr 19, 2020 4:00 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Naturally I would be the exception to the rule of coming off Lyrica easily. (I had a sleep doctor tell me that he had never had anyone have any trouble coming off of Restoril!!--not my experience.) And yes, I agree, the mix of those one-nighters makes determinations difficult. Another reason why a t...
by wantok
Sun Apr 19, 2020 3:15 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Bad report: first time I went off for two days was terrible sleep both nights. Took Xanax one night, upped my marijuana the other. Neither worked. Then started Lyrica again. Much shorter effectiveness. 50 mg for 3 nights, then 75 mg for 4, then started feeling moody. Second break much worse. Took Mi...
by wantok
Wed Apr 08, 2020 9:04 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Well, I'm going to try two nights off. And then go back to 50mg, then 75 mg, then 2 nights off. I do have to take a lot of marijuana to get to sleep so I will tank up on that.
by wantok
Wed Apr 08, 2020 1:52 pm
Forum: Prescription Medications
Topic: Lyrica questions
Replies: 19
Views: 412

Re: Lyrica questions

Thanks, Beth, for your response. Question: do you know, or does anyone out there know, if I start getting depressed on the Lyrica, is it possible to quit the drug until it is out of my body and then try it again at the lower dose, or will the depression likely start up right away at the lower dose? ...