Restless Legs Syndrome (RLS) Discussion Board

Well, I tried Dipyridamole. Not only did it not improve my symptoms but it increased my hyperawareness which made it even harder to sleep through my PLMS. That’s the opposite of what the study suggested, but I’m always in that rare group that has idiosyncratic reactions — the same thing happened to ...

That’s fantastic. It’s great to get your updates.

Sorry, for ‘norco’ in my post read ‘hydrocodone’. Also keep your dose of carbidopa/levidopa to the absolute lowest you can - ideally it should not be taken along with requip as they are from the same family - dopamine agonists - and there is a significant danger of augmentation (there is a whole sec...

I felt the same way as you when I first got responses in here to my initial cry for help: so grateful that there are people out there who would reach out to help so generously. It is so affirming when this condition can be so isolating. Sounds like your rls treatment journey has begun! Asking yourse...

I should have said that a practical step we took was to get individual single quilts so that the constant movement doesn't result in one person getting all the duvet coverage. Since moving house we are in a much smaller bed - a regular double but the individual quilts helps to keep a personal comfor...

I suspect that many with really bad RLS have felt as desperate as you describe at some stage/many stages. Like the others I feel I have made my peace with it - at least up to a point. It has definitely helped me to regard it as a journey. I would like to emphasise what others have said: in general R...

Hi mudslide, I also use Kratom as part of my system to manage my rls. I find it very effective for my rls. I have read about it being stimulating at low doses and more soporific at higher doses. I found Kratom to have an alerting effect at times and I did try increasing the dose to get to the point ...

It does have some side effects, the most immediate being weight gain. It can also cause gloominess. At higher doses i got patches of inflammation on my skin. It makes me a bit dizzy and also quite tired. I sometimes get a weird sense of weakness in one of my legs when on a higher dose also.

Yes; it is reasonably effective for rls. Especially for those who have not previously augmented on the dopamine agonist family of drugs. It often works well on its own but it can be particularly effective in conjunction with other drugs. I take a low dose of it in conjunction with a tiny dose of pra...

Plus one for the kratom suggestion. It is a fantastic as-and-when remedy and seems to support most other treatments well.

Just a couple more points: I would not expect Horizant to make much impact on his symptoms at this stage. It is worth continuing to take it for when his augmented symptoms settle down as it can take a while to kick in. My instinct would be the same as Ann’s: that it might be worth moving towards dis...

Over two months after I took my last pramipexole tablet I was still experiencing severe rls all night and got at most a few hours sleep each week. At that stage my GP prescribed OxyContin. I needed 30mg to get relief - 20mg did not help much. I started to recover once I started taking OxyContin at 3...

You haven’t said what dose of mirapexin you were actually on. In your shoes, I would be very slow to return to a dopamine agonist at this stage. Although the nausea may not be caused by the withdrawal, another symptom you describe - the legs going into spasm - almost certainly is. You have gone thro...

I didn’t experience nausea - just violently increased rls symptoms so that it wasn’t possible to lie in bed at all. Try ginger for nausea - I take chrystalised ginger. It works well. It took a long time for my symptoms to settle down after I stopped mirapexin. Starting OxyContin and getting my iron ...

I was going to suggest ginger - Chrystalised ginger is what I use. Ginger has been found to be very effective in studies - as effective as some pharmaceutical options. There are also wrist bands that apply pressure to a particular point on your wrist which is supposed to help with nausea. I used the...