Restless Legs Syndrome (RLS) Discussion Board

I really sympathise with your husband. Opioid induced insomnia was a real problem for me when I was using oxycontin to treat my legs and it was definitely dose sensitive - ie the more opioid I took the worse the insomnia. Unfortunately, I have found that kratom can also induce insomnia. Some reports...

It’s great to read of people who manage to control the dopamine agonist rather than it controlling them. You give me hope that I may manage to keep a low dose of pramipexole as part of my armory for some time to come. Thank you for posting.

I find wine far worse than spirits. My legs will tolerate whiskey or two without playing up but wine gets them going every time. I find it difficult enough to control them at the best of times - haven’t come across a neutralising agent for the effects of wine ... except time.

Sorry, just saw that Steve already mentioned the a2d drugs. My bad! They seem sometimes to be slightly less effective for those who have been through dopamine agonist induced augmentation - but may be worth a try ...

The other potential treatment option is an alpha2delta ligand such as pregabalin or gabapentin. I know these are sometimes prescribed for back pain so maybe they would help with nerve damage also? I don’t know enough about them to say but they do work well for some for rls.

Interesting that out of 16,600+ men the highest incidence of rls was 5%. I see an estimate of 10% of the population being afflicted with rls often but it does not accord with my anecdotal experience. I would say it is lower than that. I appreciate that more women than men get it but could the differ...

There is some suggestion that the alpha-2-delta ligands work less well for those who have been through augmentation (although they do work for many). They are well worth trying however. I have seen some people report that weight lifting can be helpful for rls and many, many variations of diet recomm...

PatchMD.com that is

My GP has offered me iron injections but I asked Dr Buchfuhrer about them and he does not favour them. Can’t remember why but it sounded plausible. A member of a UK forum uses iron patches that she imports from the US and her serum ferritin has increased considerably. PatchMD is the site she buys th...

It’s great that you are so proactive, Steve. I hope the tramadol er affords you some good sleep. It sounds like you could do with it.

Has anyone tried iron patches?

Steve, have you been taking breaks from the cannabis? I seem to recall you experienced a bad bout a year or two ago which you attributed to prolonged cannabis use. I’m sure you’ve thought of this but thought I’d mention it in case ... I hope you get to the bottom of the problem. Absence of joy - or ...

Oh yes, I should have listed my other drugs. My regime is complicated - usually I take pramipexole (0.044mg) and pregabalin (lyrics) - gradually reducing and now down to an almost negligible 30mg. I have just finished a 3 week break from mirapexin during which I used Kratom to control my symptoms. W...

Hi srgraves01, I am one of the two dipyridamole experimenters. Although it does not eliminate symptoms, I am very glad I take dipyridamole. It helps to make the rls more bearable and definitely improves daytime well being. In the study, many of the subjects achieved complete relief using dipyridamol...

That's affirming to hear, Ann. Most people seem to get on well with neupro. I kept thinking I must be mistaken when I found it less effective. I am currently taking a break from pramipexole - this is day 8 - and it is misery. Kratom, which used to work reasonably well, is not really dealing with the...