Restless Legs Syndrome (RLS) Discussion Board

Hello All, The abstract of my question is: Does the hour by hour pramipexole blood serum level affect the concurrent nausea level in pramipexole users? I used regular pramipexole (Mirapex) from the day my PCP diagnosed me and prescribed it in 2012 until I augmented on it in 2020 at .75mg. I then swi...

I am addressing this question to Rustsmith because we have a similar Rx regimen but I'd also love to read anyone else's response. For the past 8 months I have been taking 5 mg methadone @ 5pm and then 50 mg of Tramadol (short acting) plus kratom and Med MJ at bedtime. While this regimen didn't work ...

I also read that Tramadol is prescribed (off label) for premature ejaculation. In addition to my neurologist I also saw my urologist last week so I asked him about just that and he replied that he had never heard that before. Doesn't mean it isn't true. I had a similar effect when on 10 mg methadone...

Hi Rustsmith, I have a few questions about your 6 month regimen of switching opioids but wanted to wait until my next neurologist appointment to report on his opinion of me taking both opioids concurrently and that appointment was yesterday. As a quick update to my original post, instead of taking m...

Hello All, 57 year old male with 10 years RLS “experience”. Currently taking methadone, kratom & med marijuana. Here’s my story: I used to think I had insomnia and on sleepless nights I would often take 3 AM walks abound the block. I went to my GP for this and was prescribed Ambien which barely work...