Restless Legs Syndrome (RLS) Discussion Board

So I don't know anything about spinal cord stimulation but in treatment resistant RLS cases, one option that might make sense to explore would be intrathecal morphine (1-2 mg / 24h). I've read a couple of case reports a few years back. It is certainly an option when you can't achieve enough relief w...

Hey Beth, I think you really should look more into Cannabis. It is not a magic cure for RLS related insomnia however it can influence and improve all primary RLS symptoms. Almost all strains I use personally are imported from Canada and as far as I know they can all be ordered online in your country...

Morphine is my primary RLS opioid and it is honestly not bad however 5 mg might not be enough. The big advantage of Morphine is that it often can make you sleepy and help you fall asleep much faster. Sadly I only took a couple months until I developed a tolerance against the hypnotic properties of M...

What time of day do you take the melatonin, how much do you take, and what time do you go to bed afterward? Currently I take 3 mg of Melatonin. Right afterwards I vape some Marijuana and then normally fall asleep within 10 to maximum 20 minutes. So I basically take it directly before I go to bed an...

Okay, I guess I can now make the first prediction how the current situation will develop over the next few months. As I already feared, Melatonin still does trigger RLS symptoms and while iron tablets significantly can delay that process, it still does happen. So taking Melatonin daily is not an opt...

I think the "root cause" in many cases is simply the genetic makeup (talking about those with primary RLS who developed symptoms early). Things are maybe only slightly off balance as a child but the older you get, things get more and more out of whack. Over time this process accelerates and will aff...

Thank you Betty! Things are still looking great, having absolutely no trouble sleeping whatsoever. Two days ago, I was awake a little bit during the night but only because the opioids and the Cannabis wear off and so that I to redose to fall asleep again. The way things have changed, it still feels ...

Does any one know how to get off of Horizant safely? What is your current dose? The more and the longer you have taken Horizant, the slower you generally should taper it down unless there are urgent / compelling reasons to do it faster. Over the years, I've have almost taken 60 different psychotrop...

Qyx, One thing I'm sure you could help me with is I'm trying to find out when Horizant and methadone are at their max in my system. Is that the T-max? I haven't found any graphs or data on that and I know Dr B was trying to maximize their effectiveness in the afternoon for the first dose. Maybe I'm...

So the rebound I had was minor but the ADD medication kept me awake longer than I would have expected. However I still slept in the end and I feel fine again today. I guess ADD stimulants are just horrible for me and I knew that it is very unlikely that ADD medication would work long-term again. As ...

There is no way to predict or know if Methadone will be more or less alerting / stimulating than Buprenorphine. It is different for everyone so the only way to know is to try it. Also Methadone is way more likely to cause depression, fatigue and insomnia than Buprenorphine but without trying, there ...

Hey EeFall, I just read your first post again and now see your post from April this year that shows, that you were not able to improve your RLS much. Can you make a list with all the drugs & therapies you have tried already? Also regarding this anger thing: so Buprenorphine does stimulate different ...

Okay, I think now I have something that is an interesting update. As it turned out, the positive effect of iron tablets on my insomnia were and are limited. I already described how up & down the situation was and now I was simply waiting for the situation to stabilize, which finally happened. So at ...

Okay, too bad Dr. B. can't prescribe for you. An additional thought: have you already looked into Kratom? It works like classic opioids and can be used to "boost" the effects of pharmaceutical opioids. I would say it approx. has the potential to be as effective as 10 - 20 mg of Oxycodone (5-10 mg Me...

Belbuca is Buprenorphine. I kind of regret not trying it when I had the option to do so. I've been taking the more classic opioids like Oxycodone and Morphine from the almost the beginning but later, while I was still on a relative small dose, got offered to try Buprenorphine. That would have meant ...