Search found 707 matches

by QyX
Tue Jun 02, 2020 1:30 am
Forum: Prescription Medications
Topic: Second opinion w Dr Buchfuhrer
Replies: 31
Views: 943

Re: Second opinion w Dr Buchfuhrer

Qyx, One thing I'm sure you could help me with is I'm trying to find out when Horizant and methadone are at their max in my system. Is that the T-max? I haven't found any graphs or data on that and I know Dr B was trying to maximize their effectiveness in the afternoon for the first dose. Maybe I'm...
by QyX
Mon Jun 01, 2020 11:25 am
Forum: Prescription Medications
Topic: Cannabis
Replies: 179
Views: 9007

Re: Cannabis

So the rebound I had was minor but the ADD medication kept me awake longer than I would have expected. However I still slept in the end and I feel fine again today. I guess ADD stimulants are just horrible for me and I knew that it is very unlikely that ADD medication would work long-term again. As ...
by QyX
Sun May 31, 2020 5:03 pm
Forum: Prescription Medications
Topic: Buprenorphine vs Methadone
Replies: 4
Views: 240

Re: Buprenorphine vs Methadone

There is no way to predict or know if Methadone will be more or less alerting / stimulating than Buprenorphine. It is different for everyone so the only way to know is to try it. Also Methadone is way more likely to cause depression, fatigue and insomnia than Buprenorphine but without trying, there ...
by QyX
Sun May 31, 2020 10:07 am
Forum: Help for Relationships
Topic: For Anyone Who Thinks RLS is a Joke
Replies: 23
Views: 4259

Re: For Anyone Who Thinks RLS is a Joke

Hey EeFall, I just read your first post again and now see your post from April this year that shows, that you were not able to improve your RLS much. Can you make a list with all the drugs & therapies you have tried already? Also regarding this anger thing: so Buprenorphine does stimulate different ...
by QyX
Sun May 31, 2020 9:13 am
Forum: Prescription Medications
Topic: Cannabis
Replies: 179
Views: 9007

Re: Cannabis

Okay, I think now I have something that is an interesting update. As it turned out, the positive effect of iron tablets on my insomnia were and are limited. I already described how up & down the situation was and now I was simply waiting for the situation to stabilize, which finally happened. So at ...
by QyX
Sun May 31, 2020 8:27 am
Forum: Prescription Medications
Topic: Second opinion w Dr Buchfuhrer
Replies: 31
Views: 943

Re: Second opinion w Dr Buchfuhrer

Okay, too bad Dr. B. can't prescribe for you. An additional thought: have you already looked into Kratom? It works like classic opioids and can be used to "boost" the effects of pharmaceutical opioids. I would say it approx. has the potential to be as effective as 10 - 20 mg of Oxycodone (5-10 mg Me...
by QyX
Tue May 26, 2020 12:22 am
Forum: Prescription Medications
Topic: Second opinion w Dr Buchfuhrer
Replies: 31
Views: 943

Re: Second opinion w Dr Buchfuhrer

Belbuca is Buprenorphine. I kind of regret not trying it when I had the option to do so. I've been taking the more classic opioids like Oxycodone and Morphine from the almost the beginning but later, while I was still on a relative small dose, got offered to try Buprenorphine. That would have meant ...
by QyX
Tue May 19, 2020 11:43 pm
Forum: Prescription Medications
Topic: Lyrica -- glutamate -- Gabapentin
Replies: 3
Views: 151

Re: Lyrica -- glutamate -- Gabapentin

I just wanted to add some context. In my opinion you can't ask the question if Gabapentin increases / decreases glutamate for the reasons I outlined in my posts above. Or if I maybe try to frame it in a different way. You write: Of course this could be by something else but it seem so significant to...
by QyX
Tue May 19, 2020 9:15 pm
Forum: Prescription Medications
Topic: Lyrica -- glutamate -- Gabapentin
Replies: 3
Views: 151

Re: Lyrica -- glutamate -- Gabapentin

I did some quick google research and I honestly would be surprised, if Gabapentin doesn't have similar effects on the glutamate system than Lyrica. Orally administered gabapentin (GBP), a GABA analog and anticonvulsant that is easily absorbed and crosses the blood–brain barrier, has shown promise in...
by QyX
Tue May 19, 2020 4:00 am
Forum: Prescription Medications
Topic: Use of Mirtazapine worsening RLS
Replies: 3
Views: 191

Re: Use of Mirtazapine worsening RLS

Okay, so unfortunately this is a complicated issue. Mirtazapine will, like all other drugs with central histamine H1-receptor antagonism, can significantly worsen RLS. Additionally Mirtazapine also has additional central anticholinergic and serotonergic properties who can also be responsible for mak...
by QyX
Sat May 16, 2020 2:44 am
Forum: Prescription Medications
Topic: Getting off antidepressant to help rls
Replies: 3
Views: 154

Re: Getting off antidepressant to help rls

If you have RLS, SSRi antidepressants almost always make it much worse. I would give it a go and see how it is without the Prozac. You can also try treatment for RLS but that might not work properly Prozac present. I guess you should see a doctor about this. Stopping SSRi can be real pain, especiall...
by QyX
Sun May 10, 2020 10:47 am
Forum: Prescription Medications
Topic: Cannabis
Replies: 179
Views: 9007

Re: Cannabis

Quick update: I had another hypersomnia episode. It played out similar than the last time: again I had three days were I felt great and was functioning well. Then for some reason I couldn't sleep even though I was awake for almost 20 hours at this point. So I vaped more marijuana until my brain stop...
by QyX
Sat May 09, 2020 11:04 pm
Forum: Non-prescription Medicines, Supplements, Diet
Topic: Is it worth scrapping ever tiny bit of caffiene?
Replies: 14
Views: 835

Re: Is it worth scrapping ever tiny bit of caffiene?

I stopped all caffeine. It is horrible for me and can cause pain symptoms who are difficult to treat, even with opioids and marijuana. So I rather avoid it completely. Chocolate was highly problematic, too but since I am using medical marijuana, I tolerate it a bit better but still: I maybe buy choc...
by QyX
Sat May 09, 2020 9:48 pm
Forum: Prescription Medications
Topic: Second opinion w Dr Buchfuhrer
Replies: 31
Views: 943

Re: Second opinion w Dr Buchfuhrer

Yes, I understand that it is a tough situation you are in right now. One way to approach your current doctor is to make clear that whatever he is doing right now, you are still having a considerable amount of symptoms and that he needs to do something. It is kind of up to him to come up with ideas, ...
by QyX
Thu May 07, 2020 2:05 am
Forum: Prescription Medications
Topic: Second opinion w Dr Buchfuhrer
Replies: 31
Views: 943

Re: Second opinion w Dr Buchfuhrer

I don't think it is tolerance in your case. For some people certain opioids work just better than others. The science behind it is that while opioids all work similar, they still have different receptor profiles and can be metabolised in different ways and produce different metabolites who themselve...