Restless Legs Syndrome (RLS) Discussion Board

Sue, I just started with gabapentin last night. I have been taking either topiramate or zonisamide for migraine prevention for several years. I had to get off of topiramate last year due to the impact is was having on my ability to recall names. The zonisamide was sort of working, but I decided to a...

Hello and welcome from one of the guys on the board. I see a number of parallels between your story and mine. One difference is instead of ADHD have have severe respiratory allergies (everything in the air), so I have been on virtually every antihistamine sold during the last 50+ years (so obviously...

I am going to start this by admitting that there is still a lot that I do not understand. But here goes: Antihistamines are properly described as histamine antagonists or inverse agonists. They work by attaching to the same receptor sites as histamines, but block the channel rather than triggering i...

My theory at this point is that the levels of histamine that normally circulate in my body are far above what is normal for most people due to my allergic reactions to everything in the air that isn't gaseous. To illustrate how abnormal my reactions are, I have never been able to use benedryl and th...

My point was not so much an attempt to define pain so much as to point out that there can be a disconnect betweeen what toe doctor is thinking when they ask "are you in pain" and what most patients are thinking. The difficulty of describing WED sensations to anyone, much less a physician, ...

Perhaps this is a bit of a communication issue that you can use to your advantage once you aware of it. Most of the non-medical population thinks of pain as the "hurting" sensations from things like getting cut, getting burned or trauma. In the webinar that Dr Ondo gave on WED, he said tha...

Since I originally posted this inquiry, I have found four papers from Europe that talk about either topriamate induced RLS or zonisamide induced RLS. All four papers are very limited case studies rather than the results of large scale research. There are also papers that talk about the successful us...

It's great that you were able to get the infusion while you were still in CA. I hope that it provides you the relief that you are hoping for. I also find the way that you BP bounced around very interesting. Maybe it is an example of why we can have hypotension while the life expectancy study publish...

Unfortunately, my take on this is that GPs tend to be much more comfortable with treating bronchitis and pneumonia than WED/RLS. They see both of these lung issues on a more frequent basis and have more extensive experience with the treatments and the potential downsides of not starting aggressive t...

I usually manage to get to the gym once a week. However, I am a competition class runner and usually get in three hard workouts each week in addition to doing weights in the gym. So far, I have not seen any correlation between my RLS symptoms and either the workouts or my racing schedule. But this w...

I can think of two possible reasons why your doctor would have been hesitant to prescribe Ambien for you. I was told by my doctor that Ambien is not approved for continual use, only for occasion help. She said that the only drug in the same class of sleep aids as Ambien that is approved for continua...

When I first started college, there were two other new freshman in my department. One of them eventually became my wife and we were good friends with the other guy and eventually his wife for the next four years. At graduation we went our separate ways and lost track of each other. Fast forward more...

Sue, I agree with PB, thanks for sharing this. In my case, it could very well explain why I have always been a very light sleeper, even pre-WED. Out of curiosity, did Dr Allen give you any indication that they might have an idea of how to treat this if the current project indicates that glutamate is...

I'll add my two cents, for what it's worth. I started complaining about the onset of insomnia to my neurologist six years ago when she put me on topiramate for my migraines. I also complained about issues that I was having in my arms and torso that forced me to curl up into a fetal position, which I...

I am currently on iron supplements and the only guidance that I got from my sleep neurologist was a scribbled note on my blood work results that said "start Fe supplements". Since that time, my GP has reviewed what I am doing and agreed with my approach. I am not certain yet, but I think t...