How to tolerate ADVERSE effects of tramadol

[Icantsleep]

So I'm still stuck on a tiny dose of 25mg of tramadol at bedtime (and sometimes an overnight booster dose of 12.5mg, which is actually tolerated even less)

I literally went back on mirapex 0.0625MG AFTER I augmented 4 months ago because 75-100mg of tramadol was making me very ill .

I realize a whole different regime is likely in order , but in the interim, is there a food or method of taking the pill that might ease my extraordinarily loose stools ?

I currently take it with a thick sludge of plain oatmeal .
It sure beats taking it on an empty stomach, or with bananas or crackers or chicken broth etc.

If I take it with a fruit smoothie (I did this with the booster dose once) it is utter disaster.

I also take imodium once a week (because I cant take it every day )

While I wait to try to get coverage from another drug and obviously eliminate tramadol, is there a better way to take this medication ????

Btw, I realize there may be an undiagnosed underlying problem with my bowels, but if I dont take tramadol at all, I do not experience this side effect .
... but I sure do have crazy rebound rls

[Icantsleep]

.... I suppose if I coat the med any further , I run the risk of not getting the proper dose.

I clearly need off tramadol but I need to find something to cover rebound then replace it

Looking to get a cpap to help me breathe as well before even taking a moderate codeine dose etc ...

[ViewsAskew]

Wish I had some knowledge - unfortunately not. Because of chronic appendicitis that no one identified until it had started leaking, I had a long surgery in which lost some bits of my gastro system. Since then, some things just plain bother me. Transit time can literally be 30 minutes between ingestion and running to the loo/bathroom. It is NOT fun!

Anything you know of that does the opposite in your system?

[Icantsleep]

Wish I had some knowledge - unfortunately not. Because of chronic appendicitis that no one identified until it had started leaking, I had a long surgery in which lost some bits of my gastro system. Since then, some things just plain bother me. Transit time can literally be 30 minutes between ingestion and running to the loo/bathroom. It is NOT fun!

Anything you know of that does the opposite in your system?

Just ran to the loo 3rd time today
This is from 25mg tramadol (maybe it aggravates something not yet identified)

Codeine has the opposite effect (it slows me down drastically like it does most people)
I take codeine 7.5mg in the evening as opposed to a tramadol dose just for this reason .
I'm still hooked on that tramadol dose though , so havent had a chance to go all codeine.

I have diagnosed upper airway resistance syndrome so codeine coupled with clonazepam (and THC when I ingest it) slow my breathing more .

Basically I need a CPAP or someone watching me all night before I can tolerate another opiate.

... and I also may need a colonoscopy, but that'll need to happen later .

So darn hard to take care of myself when my kids keep getting my whole house sick .
My 1 year old has diagnosed pneumonia so she gets priority

I see neurologist Thursday and sleep specialist Friday

[QyX]

Good luck to you!

You really need to see a specialist because in your case a number of different complicated symptoms intersect.

Whatever is going on with your breathing needs to be carefully investigated and treated.

It is very uncommon and even a bit bizarre that you react so bad to even really really small doses of Codeine ... the dose you are having problems with is lower than what is given to children with severe coughing.

So something is not okay and whatever it is needs to be determined.

There are also other opioids who might less problematic for your situation, mainly Buprenorphine and Tapentadol who might be useful in your situation when you don't tolerate the classic morphine-like opioids.

[Icantsleep]

Good luck to you!

You really need to see a specialist because in your case a number of different complicated symptoms intersect.

Whatever is going on with your breathing needs to be carefully investigated and treated.

It is very uncommon and even a bit bizarre that you react so bad to even really really small doses of Codeine ... the dose you are having problems with is lower than what is given to children with severe coughing.

So something is not okay and whatever it is needs to be determined.

There are also other opioids who might less problematic for your situation, mainly Buprenorphine and Tapentadol who might be useful in your situation when you don't tolerate the classic morphine-like opioids.

I tolerate 7.5 to possibly 30mg codeine ok
I just dont tolerate enough codeine to cover going off of tramadol
I might tolerate enough codeine for baseline rls, but I have trouble covering the rebound rls from zero tramadol.
The same thing actually happened with kratom once.

It is the overnight/extra coverage / combined with clonazepam/ combined with vaped indica dose of low opiate that cause the breathing problem
I have not vaped in a good 5 days because I was very sick

Perhaps I'd be able to breathe better on codeine without the THC (or better yet, I obviously would breathe better)

Tramadol is very effective in terms of controlling rls symptoms, but is essential POISON to my body .
It's too bad because it seems to be fine in terms of breathing

I just had my worst night in terms of rls in many weeks .
Not sure to attribute it to taking too much sludgy oatmeal with my tramadol (it was as if I didnt even take it)
... the night before I took it with much less oatmeal and had the frequent loo trips as described above

I cant win with tramadol
Take enough for rls and get sick
Dont take enough and have rls keep me awake

I do not think upping my newly resumed 0.0625mg of mirapex is the answer
... perhaps I'm already beginning to slowly augment again after a mere 2 weeks of taking it

I think a CPAP and elimination of tramadol are immediate priorities
I would possibly entertain a micro dose of buprenorphine
.... not sure if anyone will write the prescription though

[QyX]

Also look into Tapentadol, it is similar to Tramadol but still different enough that it might fix your RLS but not cause the problems you are currently having with Tramadol.

Tapentadol is a moderate potent opioid, right in the middle between Tramadol and Morphine. You should look into this. Maybe it is worth a shot when you can get a prescription for it.

[Icantsleep]

Also look into Tapentadol, it is similar to Tramadol but still different enough that it might fix your RLS but not cause the problems you are currently having with Tramadol.

Tapentadol is a moderate potent opioid, right in the middle between Tramadol and Morphine. You should look into this. Maybe it is worth a shot when you can get a prescription for it.

I did look into this

Seems 50mg is the smallest dose when I asked the pharmacist and with other brief research
Would be more ideal at the 25mg and halved (or even quartered into multiple doses)

No one else even gave it a second thought

Neupro patch or continue with current regime or you're welcome to find someone else or you're welcome to try something else on your own
... hints of methadone but I still think that's a long way off

... although I didnt ask my GP
Maybe he would prescribe
(Would rather try tapentadol... I think (?))

**** edit

I should mention that I have finally adjusted to 25mg of tramadol
A combination of probiotics in yogurt, going without my PPI for three weeks , and developing an all around tolerance (because it sure doesnt cover me for rls)

I definitely need more symptom coverage
While I may tolerate another 12.5mg , I'd like to attempt to replace with codeine
.... I'm still
codeine7.5mg /sativa/
mirapex 0.0625mg(!?!)/tramadol 25mg /clonazepam 0.5mg /indica/
wake up/clonazepam 0.25mg/CBD oil /indica/
wake up/codeine 15mg

Getting a CPAP Saturday afternoon and will look to make the switch soon after

[Bridgercan]

Getting a CPAP Saturday afternoon and will look to make the switch soon after

Hey Icantsleep—wondering if you got your cpap and how cpap therapy is going? Hope it’s making a difference for you; you’ve got a lot of challenges going on. So good on you for staying in the fight for yourself and your family. May you find your way out of the fiendishly frustrating health maze you’re in!

I ask because I started cpap therapy last November for obstructive sleep apnea. What I’ve discovered in the meantime is after having had to increase my opioid dose while getting off Neupro patch, most nights I just couldn’t tolerate it—not even for two minutes. I felt like I was suffocating inside the mask.

This happened about five weeks into cpap therapy. I’d just gotten all the settings dialed in and found a comfortable, well-fitting mask (returned the first three). I was sleeping better and was starting to feel somewhat rested in the morning. Weirdo that I am, I actually began to like putting on the mask at bedtime, in spite of my spouse’s Hannibal Lecter/Darth Vader jokes.

Then I began augmenting on the patch—GRRR!—and my nights went down the toilet: if I took enough oxy to keep my legs happy, I couldn’t tolerate cpap and woke up feeling lousy, like bad hangover lousy. If I dialed back the oxy enough to tolerate cpap, my legs would wake me every time I fell asleep.

Good news is, having been off Neupro for seven weeks, I’m now able to dial back the oxy almost to my old dosage. I’m starting to tolerate cpap long enough each night that it’s beginning to help again.

On a side note, my sleep specialist would like to see me transition to methadone only. I’m giving it serious thought.