Use this section to discuss your experiences with prescription drugs, iron injections, and other medical interventions that involve the introduction of a drug or medicine into the body. Discuss side effects, successes, failures, published research, information about drug trials, and information about new medications being developed.

Important: Posts and information in this section are based on personal experiences and recommendations; they should not be considered a substitute for the advice of a healthcare provider.
Post Reply
Posts: 97
Joined: Fri Apr 01, 2016 3:14 pm


Post by wantok »

Anyone heard of anyone who got depressed on both gabapentin and lyrica, NOT get depressed on Horizant? (I know we are all different.)

Posts: 5628
Joined: Tue Mar 10, 2009 4:20 pm
Location: Northwest Territories, Canada

Re: Gabapentin--Lyrica--Horizant?

Post by badnights »

I doubt if anyone who got depressed on gabapentin would want to try Horizant. It is a pro-drug of gabapentin that becomes gabapentin in the body, so I don't imagine it would behave much differently. It was developed to deal with the erratic absorption of gabapentin, so consistency of effect would be the main difference.

I doubt a doctor would prescribe Horizant to someone who had become depressed on gabapentin. But maybe I'm wrong.
Beth - Wishing you a restful sleep tonight
I am a volunteer moderator. My posts are not medical advice. My posts do not reflect RLS Foundation opinion.

Post Reply