RLS and Adrenaline - it's an ill wind ...
Posted: Sun Dec 30, 2018 11:20 am
I am going through a difficult relationship breakdown which is throwing up all sorts of very worrisome issues. This has caused me to experience pronounced fight or flight symptoms on a more or less daily basis over the last 3 or 4 months. These often occur most significantly in the evening as time zone differences mean that difficult communications take place at that time. I get surges of adrenaline causing heart palpitations and nausea (to the extent that I paid for a private heart examination which fortunately gave my heart a clean bill of health but confirmed the palpitations and attributed them to adrenaline). The thing is that my rls symptoms have been virtually non-existent over that time. In particular I notice that on nights when I get a particular shot of adrenaline (some more bad news/unpleasant interactions), my rls disappears completely. On nights when I have less significant adrenaline symptoms come through although mildly.
Things have been so good (rls-wise) that in the last week or so I have eliminated my pramipexole and am now only taking dipyridamole and ldn. Even though I had been taking pramipexole daily which I would have thought would mean exacerbated symptoms when it was reduced/eliminated, the symptoms I am now experiencing could at the highest be described as mild and, as I say, when a big shot of adrenaline comes through in the evening, they are non-existent. The only other changes I have made are: (1) I have started to use iron patches as well as iron bisglycinate every other day; (2) I have introduced a daily dose of glucosamine; (3) I have been eating a lot less and have lost quite a bit of weight but my diet remains varied - fairly healthy with whole foods etc but also some high sugar elements.
Has anyone else noticed a connection between high adrenaline and rls? I saw a post on another website of someone noticing an improvement in their rls when being treated with mirabegron, a drug that assists with bladder control by operating on the adrenal system, and wondered - in my non-sciency way - if this provided some sort of support to the theory.
Things have been so good (rls-wise) that in the last week or so I have eliminated my pramipexole and am now only taking dipyridamole and ldn. Even though I had been taking pramipexole daily which I would have thought would mean exacerbated symptoms when it was reduced/eliminated, the symptoms I am now experiencing could at the highest be described as mild and, as I say, when a big shot of adrenaline comes through in the evening, they are non-existent. The only other changes I have made are: (1) I have started to use iron patches as well as iron bisglycinate every other day; (2) I have introduced a daily dose of glucosamine; (3) I have been eating a lot less and have lost quite a bit of weight but my diet remains varied - fairly healthy with whole foods etc but also some high sugar elements.
Has anyone else noticed a connection between high adrenaline and rls? I saw a post on another website of someone noticing an improvement in their rls when being treated with mirabegron, a drug that assists with bladder control by operating on the adrenal system, and wondered - in my non-sciency way - if this provided some sort of support to the theory.