Published Research - General Sleep and RLS (WED)

For everything and anything else not covered in the other RLS/WED sections.
ViewsAskew
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Re: Published Research - General Sleep and RLS (WED)

Postby ViewsAskew » Fri Apr 27, 2018 10:10 pm

Ann - Take what you need, leave the rest

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Rustsmith
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Re: Published Research - General Sleep and RLS (WED)

Postby Rustsmith » Fri Apr 27, 2018 10:59 pm

I saw this the other day. Interesting observation, but they couldn't tell if this is a cause, an effect or simply a statistical fluke.
Steve

Augmentation Evaluation http://bb.rls.org/viewtopic.php?f=4&t=9005

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ViewsAskew
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Re: Published Research - General Sleep and RLS (WED)

Postby ViewsAskew » Fri Apr 27, 2018 11:02 pm

Rustsmith wrote:I saw this the other day. Interesting observation, but they couldn't tell if this is a cause, an effect or simply a statistical fluke.


Correct. And the n was quite small.
Ann - Take what you need, leave the rest



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ViewsAskew
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Re: Published Research - General Sleep and RLS (WED)

Postby ViewsAskew » Sun Jun 03, 2018 4:37 am

PLMS in RLS patients causes blood pressure changes. Small n (only 10); author stated more studies need to be done. "Ahmed also notes this assessment is only the first step in understanding the link between sleep disorders and cardiovascular problems. He says, “We need more data and studies before we can conclude the clinical relevance and implications of sleep disorders on cardiovascular health.” "

http://www.sleepreviewmag.com/2018/06/r ... e-changes/
Ann - Take what you need, leave the rest



Managing Your RLS



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Polar Bear
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Re: Published Research -

Postby Polar Bear » Tue Jun 26, 2018 10:27 am

Nerve Decompression Surgery thought to help RLS Symptoms.

https://www.ncbi.nlm.nih.gov/pubmed/28729849
Betty
http://www.willis-ekbom.org/about-rls-wed/publications
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ViewsAskew
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Re: Published Research -

Postby ViewsAskew » Tue Jun 26, 2018 8:20 pm

Polar Bear wrote:Nerve Decompression Surgery thought to help RLS Symptoms.

https://www.ncbi.nlm.nih.gov/pubmed/28729849


Interesting...and makes me wonder how often neuropathy is comorbid with RLS as well as how often RLS may be mistaken for neuropathy.
Ann - Take what you need, leave the rest



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Polar Bear
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Re: Published Research - General Sleep and RLS (WED)

Postby Polar Bear » Tue Jun 26, 2018 9:34 pm

I have at times over the years, had spells when there was burning on my feet. That just disappeared a few years ago. Nowadays I have times when there is a burning sensation on my lower legs usually just before the RLS symptoms break through.
Betty
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Another link with cardiovascular health

Postby badnights » Sun Jul 01, 2018 5:09 am

From https://www.sciencedaily.com/releases/2 ... ceDaily%29

"Poor sleep quality appears to be an important risk factor for atrial fibrillation, report scientists in the first study of its kind to demonstrate a relationship between poor sleep quality independent of sleep apnea and a higher risk of atrial fibrillation (AF). Their findings are published in HeartRhythm.

AF is an irregular, rapid heart rate that may cause symptoms such as heart palpitations, fatigue, and shortness of breath. It can substantially reduce quality of life and is associated with heightened risks of stroke, dementia, heart attack, kidney disease, and death. Obstructive sleep apnea has been established as a risk factor for AF, but the mechanism is unclear. While episodes of abnormally slow or shallow breathing (hypopnea) and apnea may cause cardiopulmonary stress, induce inflammation, and contribute to cardiovascular disease, obstructive sleep apnea also results in poor sleep. Aspects of poor sleep such as altered sleep duration, efficiency, and architecture have been linked to other cardiovascular diseases.

"While a relationship between sleep apnea and AF has previously been demonstrated, the effect of sleep itself on AF risk has remained unknown," explained lead investigator Gregory M. Marcus, MD, MAS, Electrophysiology Section, Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA. "Strategies to enhance sleep quality are different from those that focus on relieving airway obstruction, so it is important to understand the relationship between sleep itself and AF."

Investigators drew on four different studies to determine whether poor sleep itself is a risk factor for AF. First, they used the global, internet-based Health eHeart Study and determined that individuals with more frequent nighttime awakenings while trying to sleep more often carried a diagnosis of AF. They then validated these findings by using the NIH-funded Cardiovascular Health Study, a prospective cohort study, in which they found that individuals who reported more frequent nighttime awakenings at baseline exhibited a higher risk of developing AF both before and after adjustment for potential confounders.

Within a subset of these individuals who had undergone formal sleep studies, they found that less REM sleep in particular predicted future AF. Finally, in order to see if these findings were readily translatable to patients already seen in healthcare settings and recognized by their providers as having sleeping difficulty, they drew on the California Healthcare Cost and Utilization Project (HCUP), a set of medical records databases of all California residents aged 21 or older who received care in a California ambulatory surgery unit, emergency department, or inpatient hospital unit between January 2005 and December 2009. Among several million people, the HCUP data confirmed that a diagnosis of insomnia predicted a diagnosis of AF both before and after adjustment for potential confounding effects.

These results provide more evidence that sleep quality is important to cardiovascular health and specifically to AF. Investigators determined that there was no evidence that sleep duration per se was a risk factor for AF. Instead, they consistently found sleep disruption to be an important risk factor. While the underlying mechanisms are still unknown, these findings may motivate novel ways to think about, and hence future research into, factors that influence AF risk.

This is the first study to demonstrate a relationship between worse sleep quality independent of sleep apnea and a higher risk of AF. "These data provide compelling evidence that sleep quality itself, even independent of sleep apnea, is an important determinant of AF risk," noted Dr. Marcus. "While there are several available treatments for AF, prevention of the disease would be ideal. The good news is that sleep quality can be modifiable and is something that at least to some degree is under the control of the individual. It's possible that improving sleep hygiene, such as performing regular exercise, getting to bed at a reasonable hour on a regular basis, and avoiding viewing screens before bed as well as caffeine later in the day, might help stave off AF.""
Beth - Wishing you all restful sleep tonight
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