You might want to sit down and think about what to do next.. It sounds like you are becoming desperate for help. Going to a neurologist may be a good next step, as they tend to handle RLS more often than GP's do from my understanding..
However that is probably a whole new bag of worms.. You'll likely be put through the medicine treadmill where they will want to give you anything but opiates, even after all the other meds are possibly proven ineffective..
I don't mean to scare or upset you. There is a good chance Requip or Mirapex could work just fine for you, maybe even clonazepam. But if they don't, or you can't even get them to give you ANY of those meds; be prepared to do some hard research and start contacting doctors you can find who list themselves as able to deal with RLS, or RLS experts.
If you can get to California rather easily, it might be worth it to try to see Dr. B also (
www.rlshelp.org)
I have also dealth with varying degrees of depression, and personally I don't see how it could effect RLS, unless your depression is causing you to display anxiety / you worry about your RLS and it is always on your mind, etc.. Constantly thinking about RLS probably does make it worse more often than not, as with many other illnesses.
Whatever you do however, DO NOT let them stuff anti-depressants down your throat unless it is possibly Wellbutrin, or maybe even Luvox.. I can't endorse them either way but my experience with Luvox leads me to believe it didn't effect my RLS one way or the other.. However since I also take opiates it is also hard for me to tell overall since any irritation brought on would likely be covered up by the opiates.
Wellbutrin is thought to be an RLS friendly drug, so may be worth a shot, and if you are currently taking any anti-depressants (doesn't sound like you are) you may want to consider stopping them for a short while to see if your RLS improves..
Try eliminating caffeine and artificial sweeteners from your diety also. If you smoke, try to cut back or stop. Smoking irritates my RLS even when I am fully medicated sometimes. And when I has none in the past, it was brutal and instantaneous with every inhalation.
My advice to you, if you are not being treated for depression and DO NOT feel suicidal.. Don't tell ANYONE in the medical field unless it gets super bad or until you secure medication that works but are still severely depressed. Unless you are willing to gamble depression meds making you RLS worse, when doctors find out an RLS patient is depressed they almost immediately give RLS a backseat and claim the patient is simply depressed and needs treatment, instead of recognizing that the depression is likely CAUSED by the suffering the RLS patient is going through because of their symptoms and lack of sleep. I think I've even seen posts on the net from peoples whose doctors claimed the RLS was caused by the depression, or flat out downplayed the RLS and tried to make the patient forget about it by continually bringing up the depression
