Anti-inflammatory medications

[nomoboh]

I had added mobic to my nightly regimen,(gabapentin, clonazepam, melatonin) due to chronic pain. I recently had a bout of pancreatitis which of course affects liver function, and now they tell me I have "early and mild," cirrhosis, whatever that means. Post-hospitalization they advised me to stop taking any and all nsaids. When I was taking it, I was sleeping through the night most nights, but since I stopped, I have been up every single night.

This all leads me to wonder if anyone has explored the possible role chronic inflammation in RLS, or if anyone has any experience with nsaids as an adjunct to therapy?

Thanks!

[Polar Bear]

On occasion I use Ibuprofen because chronic pain can waken me during the night. Even though one of my consultants does not approve of NSAIDs. But sometimes needs must though I do try to avoid it as far as possible. This is what I do, I am not saying I recommend it. My experience only.
Modic is much stronger and is prescription only.

[debbluebird]

I would like recommendations for anything anti-inflammatory besides NSAIDS.

[Lissa496]

I take ashwagandha. I only take 100 mg. It is supposed to help RLS and have some anti-inflammatory. Here is a link: https://www.medicalnewstoday.com/articles/318407#uses
https://www.webmd.com/diet/health-benefits-ashwagandha

[Frunobulax]

This all leads me to wonder if anyone has explored the possible role chronic inflammation in RLS, or if anyone has any experience with nsaids as an adjunct to therapy?

Some people believe in chronic inflammation as root cause of RLS. Inflammation does inhibit iron transport, moving iron out of the cells and into iron storages. But to my knowledge there is little or no research either backing this up or refuting it.

[paulawesterlund]

see the discussions under non prescription medications. Someone there recommended 2 chinese
traditional medicines and I remember an account of a chinese woman using them and becoming
free of RLS for the lst time in her long life. I personally make tea from nettles and drink it as an
anti-inflammatory and it also fights cardiovascular diseases. Now its just coming up in the midwest and so its very tender.

[netadmin67]

Ashwagandha helps me. Also, I think that inflammation is a large component or possibly a cause of RLS - just my opinion from years of suffering and experimenting.

[Rustsmith]

Netadmin, I am not disagreeing with your statement but I just wanted to add that the medical definition of inflammation is so broad that it can include just about (but not quite all) diseases and disorders. With such a broad definition, diseases such as multiple sclerosis and arteriosclerosis are inflammatory diseases. Therefore, even though the root cause of RLS is brain iron deficiency, some of the causes of this deficiency in some people may be due to inflammation. For others, it may be due to a geneticaly malformed protein that is limiting iron transport across the blood/brain barrier, which would probably not be classed as inflammation