Search found 198 matches

by Frunobulax
Tue Nov 12, 2019 10:39 am
Forum: Non-prescription Medicines, Supplements, Diet
Topic: Vitamin D3- when’s the best time to take it?
Replies: 3
Views: 65

Re: Vitamin D3- when’s the best time to take it?

There is a study in Hawaii with healthy people averaging 28 hours of sun exposure per week. Half of them were deficient in Vitamin D. https://www.ncbi.nlm.nih.gov/pubmed/17426097 IMHO it's a very good idea to have a high vitamin D level (70 to 100), as we are just starting to realize how important i...
by Frunobulax
Sat Nov 09, 2019 1:17 pm
Forum: General Topics: RLS/WED
Topic: Question: RLS and blood markers
Replies: 10
Views: 196

Re: Question: RLS and blood markers

(somehow quotes got mixed up in my first post. I tried to repair it, but it's still possible that I got some text shifted to the wrong quotes.) consequences of insulin resistence, mechanics of silent inflammation and the role of carbohydrates (which we eat a lot more than 50 years ago) and polyunsat...
by Frunobulax
Tue Oct 22, 2019 9:12 am
Forum: Just Joined?
Topic: 1st post after 24 years of RLS
Replies: 62
Views: 1057

Re: 1st post after 24 years of RLS

Inflammation of what ? My gut ? [...] Any suggestions as to what I should be doing differently? Silent inflammation may not be visible, it shows up only in some blood markers. Basically your immune system is stimulated to attack your own cells, and we have some theories about this, but nothing defi...
by Frunobulax
Tue Oct 22, 2019 8:49 am
Forum: Physical Treatments
Topic: How to be a guinea pig?
Replies: 9
Views: 329

Re: How to be a guinea pig?

That being said, is there any feasible way I can offer myself up as a guinea pig for these or any other relatively novel treatments? Do we know of any doctors or companies looking for weirdos like me willing to do this? I was wondering the same a few years ago. I couldn't find anything. Your best s...
by Frunobulax
Fri Oct 18, 2019 1:01 pm
Forum: General Topics: RLS/WED
Topic: Question: RLS and blood markers
Replies: 10
Views: 196

Re: Question: RLS and blood markers

Frunobulax wrote:
  • The BID theory (BID drives inflammation)


should be BID drives RLS of course.
by Frunobulax
Fri Oct 18, 2019 12:55 pm
Forum: Non-prescription Medicines, Supplements, Diet
Topic: Fasting, keto and lectin free diet
Replies: 5
Views: 418

Re: Fasting, keto and lectin free diet

I’ve been away from the forums for some times now as my RLS has been under control. To get here I went on a low fodmap diet. True, I missed that, thanks for the hint. FODMAP is another thing that may cause weird symptoms for a lot of us. I'm not as well acquainted with low fodmap as I should be (pe...
by Frunobulax
Fri Oct 18, 2019 12:48 pm
Forum: Non-prescription Medicines, Supplements, Diet
Topic: Fasting, keto and lectin free diet
Replies: 5
Views: 418

Re: Fasting, keto and lectin free diet

Good food: ⋅  Olive oil, coconut oil, linseed oil, avocados. So if I recommend something, I'll try to keep you updated if I learn new things :) Recently I found some pretty strong evidence that polyunsaturated fats should be avoided and saturated fats (animal fat/butter and coconut oil) a...
by Frunobulax
Fri Oct 18, 2019 12:24 pm
Forum: Augmentation
Topic: Is Tramadol continuing my Mirapex augmentation?
Replies: 46
Views: 1238

Re: Is Tramadol continuing my Mirapex augmentation?

I do really wish I had low iron My blood iron was the only recent concern with my bloodwork in that it was too high It's been a little too high for quite some time apparently Are we talking about Ferritin or Transferrin%? Ferritin is an inflammation marker. There are studies (with rats I think, but...
by Frunobulax
Fri Oct 18, 2019 12:14 pm
Forum: Augmentation
Topic: Is Tramadol continuing my Mirapex augmentation?
Replies: 46
Views: 1238

Re: Is Tramadol continuing my Mirapex augmentation?

b) you augment under Tramadol. Tramadol is the only opioid where this can happen. One way to test for it would be to slightly increase the dose, let's say from your current 100 mg / day to 150 mg / day. When you have more symptoms afterwards, you certainly have some form of augmentation and when yo...
by Frunobulax
Fri Oct 18, 2019 11:53 am
Forum: Prescription Medications
Topic: Medication for irregular use
Replies: 15
Views: 306

Re: Medication for irregular use

I would not use Sinemet. I believe that you augment more quickly with it rather than mirapex. .125mg is even a lower dose used for mirapex. Personally, I would use an opioid for those 15 nights or so. Sinemet (which is L-Dopa I think?) and mirapex doses are not comparable at all. For me, .18mg Mira...
by Frunobulax
Fri Oct 18, 2019 11:34 am
Forum: Prescription Medications
Topic: Medication for irregular use
Replies: 15
Views: 306

Re: Medication for irregular use

L-dopa can only be used infrequently. It will cause augmentation very quickly, in some cases as quickly as a few days. Using it like you do where you only use it 2 or 3 times a month is fine. Using it as a supplement for special circumstances, such as long airline flights or attending a child's rec...
by Frunobulax
Fri Oct 18, 2019 9:49 am
Forum: General Topics: RLS/WED
Topic: Question: RLS and blood markers
Replies: 10
Views: 196

Re: Question: RLS and blood markers

As stated earlier, conclusions cannot be drawn from a single example. But in my case, my RLS before I retired was moderate at its worst. I only remember issues occurring during the frequent very long airline flights that I had to take. My job also involved a huge amount of stress. My RLS went to ve...
by Frunobulax
Thu Oct 17, 2019 12:07 pm
Forum: General Topics: RLS/WED
Topic: Question: RLS and blood markers
Replies: 10
Views: 196

Re: Question: RLS and blood markers

Oh, one more thing. I've heard from several patients with RLS that cortisone gave them complete relief from RLS. As cortisol is one of the most potent anti-inflammatory agents, that's another clue to an inflammation connection (for some patients at least). Also stress highly correlates with RLS, and...
by Frunobulax
Thu Oct 17, 2019 11:55 am
Forum: Prescription Medications
Topic: Medication for irregular use
Replies: 15
Views: 306

Re: Medication for irregular use

Anyone have any ideas of a drug I can take irregularly to deal with my RLS? Why not L-Dopa? It quickly loses efficiency for some of us, L-Dopa didn't do anything for me when I was taking DAs. But now that I'm on Oxycodone (for over 4 years) I found that 100mg L-Dopa (extended release) is fairly eff...
by Frunobulax
Wed Oct 16, 2019 7:08 pm
Forum: General Topics: RLS/WED
Topic: Question: RLS and blood markers
Replies: 10
Views: 196

Re: Question: RLS and blood markers

That also explains why doctors like Steven Gundry report that 100% of his autoimmmune patients are severely deficient in vitamin C. Vitamin D, not vitamin C. (Sometimes it's quite unnerving that I can't edit my own posts after an hour or so.) Also coenzyme Q10 is in the same boat, antioxidant that ...

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